Was this helpful?
Thumbs UP Thumbs Down

What to Know About Grey’s Anatomy Season 22


Ellen Pompeo
Table of Contents
Close up of stethoscope and doctor writing a prescription in the blurred background.

Inside Grey’s Anatomy Season 22

As the series heads into its 22nd season, fans remain hooked on the lives of the doctors at Grey Sloan Memorial. From high-stakes surgeries to deep personal relationships, the show has without a doubt evolved.

But what’s next for Grey’s Anatomy? The upcoming season promises to delve deeper into both the medical and personal lives of the staff, while maintaining the core elements that made the show a favorite.

Medical workers in a laboratory.

Show Overview

Grey’s Anatomy is a long-running American medical drama. Originally premiering on ABC on March 27, 2005, the series revolves around the lives of surgical interns, residents, and the patients at Grey Sloan Memorial Hospital in Seattle.

The show is known for its blend of complex medical cases and intricate personal relationships. Themes of love, loss, and ambition are explored.

Close up of calendar page on office desk.

Season 22 Status

ABC has given the green light for a 22nd season of Grey’s Anatomy. The upcoming season is expected to premiere in the fall of 2025.

This renewal comes as season 21 moves towards its end. Grey’s Anatomy has maintained a robust streaming presence despite the decline in live viewership over the years, hinting at the series’s continued legacy.

Ellen Pompeo at the premiere of Grey's Anatomy.

Return of Meredith Grey

Ellen Pompeo has expressed her intention to remain involved with Grey’s Anatomy for both fictional and emotional reasons. In a recent interview, she shared that leaving the series entirely wouldn’t be “sensible.”

She continued to add, “If I were to walk away completely, everybody gets to make money from my hard work for 20 years. And I wouldn’t make any money.”

camilla luddington at the elton john academy awards viewing party

Cast Expectations

With Grey’s Anatomy returning for a 22nd season, several beloved characters are set to make a return. Chandra Wilson, Kevin McKidd, Camilla Luddington, Caterina Scorsone, and Kim Raver will be reprising their respective roles.

These returning cast members are expected to add depth and continuity to the series. With the inclusion of these members, the series maintains its strong connection with its audience.

trevor jackson  actor

New Additions

Trevor Jackson appeared in the penultimate episode of Grey’s Anatomy Season 21, which aired on May 8, 2025.

His character is described as a “handsome, intelligent, but arrogant man in his late 20s who has just moved to Seattle.” It should be noted that specific details about his character’s profession remain undisclosed.

Ellen Pompeo at the TGIT Premiere

Showrunner Insight

Meg Marinis is the current showrunner of Grey’s Anatomy. She has emphasized that Meredith Grey remains a vital part of the series even as Ellen Pompeo’s on-screen appearances have become less frequent.

According to Meg, Meredith’s essence continues to influence the narrative. She added, “I hope that we don’t ever have to see a ‘Grey’s’ without Meredith every now and then.”

Camera on stand behind the screen.

Plot Direction

In season 22, Grey’s Anatomy is set to shift its focus back to the central elements that made the series a hit. The upcoming season is expected to return focus to the dynamics between interns, residents, and their mentors at Grey Sloan Memorial Hospital.

The upcoming season is expected to shed light on a new generation of medical professionals. They will be seen navigating the complexities of their careers and personal lives.

Couple holding hands at sea sunset.

Romantic Storylines

Season 22 is expected to continue exploring the evolving romantic dynamics among its characters. A particular focus is going to be on Jo Wilson and Atticus Link Lincoln.

Their relationship has been a central storyline in recent seasons. The couple will likely face new challenges as their storyline continues into Season 22, exploring themes of partnership and parenthood in the relationship.

Doctor in white coat with stethoscope

Medical Cases

In season 22, Grey’s Anatomy is once again set to continue its tradition of high-stakes medical cases that challenge the skills and ethics of its doctors. The show has done a splendid job of blending complex medical scenarios with personal drama.

The audience is kept engaged and emotionally invested. It should be noted that specific details for season 22 remain under wraps.

Professional film and video camera on the set

Behind-the-Scenes

The cast and crew of Grey’s Anatomy have established a strong on-set community. Behind-the-scenes moments give an insight into how the team celebrates milestones.

These glimpses give fans a richer connection to the series. Celebrations often revolve around the series hitting a certain episode number, and heartfelt messages are shared on social media platforms.

Hulu logo

Streaming Availability

Grey’s Anatomy is widely accessible across multiple streaming platforms. This allows fans to catch up on past seasons and stay current with new episodes.

The series is available on Hulu, Netflix, ABC, and other live streaming platforms. On Hulu, all 21 seasons are available, with new episodes of the recent season released for next-day streaming.

Man is using laptop with black keys social media icons

Critical Reception

Grey’s Anatomy season 21 has led to a range of reactions from both critics and viewers. Some viewers have praised the acting of new cast members like Adelaide Kane.

However, others have expressed dissatisfaction with performances and the show’s direction. One reviewer criticized the emphasis on inclusivity, suggesting it “detracts” from the main plot.

Blood pressure meter and medical equipment.

Cultural Impact

Grey’s Anatomy has undoubtedly left a lasting mark on popular culture since its debut in 2005, profoundly shaping public perceptions of healthcare and hospital life.

Patrick Dempsey’s portrayal of Dr. Derek Shepherd has inspired countless viewers to pursue careers in the medical field, highlighting the show’s powerful influence beyond entertainment.

Meanwhile, fans are thrilled as Hulu’s Paradise has officially been renewed for Season 2, sparking excitement for what’s to come.

Emmy Award statues

Awards and Recognition

Grey’s Anatomy has gained numerous prestigious awards over its extensive run. From the Golden Globe Awards, the Primetime Emmy Awards, to the People’s Choice Awards, the series has won them all.

Besides Grey’s Anatomy, these 15 exciting HBO series coming in 2025 have kept the fans waiting in anticipation.

What do you think will happen in the upcoming season? Let us know in the comments down below.

Read More From This Brand:

Don’t forget to follow us for more exclusive content right here on MSN.

If you liked this story, you’ll LOVE our FREE emails. Join today and be the first to get stories like this one.

This is exclusive content for our subscribers

Enter your email address to subscribe and get instant FREE access to all of our articles

Was this helpful?
Thumbs UP Thumbs Down
Prev Next
Share this post

Lucky you! This thread is empty,
which means you've got dibs on the first comment.
Go for it!

Send feedback to NashvilleGab

Close Feedback Form



    We appreciate you taking the time to share your feedback about this page with us.

    Whether it's praise for something good, or ideas to improve something that isn't quite right, we're excited to hear from you.